The Latest: A Nepalese woman with her child waits for a bus to go back to her village a day prior to lockdown in Kathmandu, Nepal.

DES MOINES, Iowa — With interest in coronavirus vaccines lagging in much of Iowa, public health officials plan to make shots available at gathering spots like farmers markets and sports events. Gov. Kim Reynolds said Wednesday that the state is talking with groups including the Iowa Cubs baseball team and the Des Moines Downtown Farmers Market about holding mass vaccination clinics at those sites.

A Nepalese woman with her child waits for a bus to go back to her village a day prior to lockdown in Kathmandu, Nepal, Wednesday, April 28, 2021. Tens of thousands of people left the Nepalese capital Wednesday a day ahead of a 15-day lockdown imposed by the government because of spiking cases of COVID-19 in the country. The lockdown has been imposed in most of the major cities and towns in the country.
Health worker Adrian Hernandez, right, helps Isadora Davila after she returned home from a hospital in Salto, where she was treated for COVID-19, in Belen, Uruguay, Wednesday, April 28, 2021.
Maggie Sedidi
Health care worker Maggie Sedidi, receives a Johnson & Johnson COVID-19 vaccine at a vaccination center in Soweto, South Africa. South Africa has resumed giving the Johnson & Johnson vaccine to health care workers after a more than two-week pause in the use of the only COVID-19 inoculation in the country. South Africa on Wednesday, April 28 restarted its drive to inoculate 1.2 million health care workers with the vaccine.
A municipal official, second right, reprimands street vendors for not wearing face masks properly during a lockdown imposed due to rising number of COVID-19 cases in Bengaluru, India, Wednesday, April 28, 2021. India, a country of nearly 1.4 billion people, Wednesday became the fourth nation to cross 200,000 deaths.
Michael Gebhardt from the German Armed Forces vaccinates an employee of Sander AG in Schwarzenbach an der Saale, Germany, Wednesday, April 28, 2021. Employees will be vaccinated against Covid-19 in vaccination booths built by Sander AG starting Wednesday.(Daniel Vogl/dpa via AP)
People visit fields of blooming tulips on display in the Emirgan Park in Istanbul, Wednesday, April 28, 2021, a day before the latest lockdown to help protect from the spread of the coronavirus. As cases and deaths soar, Turkey is going into a full lockdown Thursday and last until May 17. Residents will be required to stay home except for grocery shopping and other essential needs, while intercity travel only will be allowed with permission. Restaurants are allowed to deliver food.
Kashmiri women receive COVISHIELD vaccine for COVID-19 at a primary health center in Srinagar, Indian controlled Kashmir, Wednesday, April 28, 2021. India, a country of nearly 1.4 billion people, Wednesday became the fourth nation to cross 200,000 deaths.
Medical staff wheel a bed with a COVID-19 patient into the intensive care ward of the Erasme hospital in Brussels, Wednesday, April 28, 2021.
People stand in line, resumes in hand, while waiting to apply for jobs during an outdoor hiring event for the Circa resort and casino, Tuesday, April 27, 2021, in Las Vegas. The casino was looking to hire around a hundred hospitality workers.
A doctor tells relatives of a COVID-19 victim that the person has died, at the ICU of the National Hospital in Itaugua, Paraguay, Wednesday, April 28, 2021.
Staff members wearing protective masks demonstrate their safety measures to the media at a mahjong parlor in Hong Kong, Wednesday, April 28, 2021, to comply with the ” Vaccine Bubble” requirements by the government to resume their business. Hong Kong health officials announced that they will relax COVID-19 social distancing measures starting on Thursday. It will include reopening bars and nightclubs, extending dining hours and allowing more diners per table, under the circumstances that customers and venue staff have been vaccinated.
Nurse Luigi Lauri prepares a dose of the Pfizer vaccine for 85-year old Giorgio Tagliacarne at his home in Rome, Tuesday, April 27, 2021. The doctor and nurse manage just 12 shots a day _ six in the morning, six in the afternoon _ making house calls to Rome’s homebound elderly to administer coronavirus vaccines and along with them, the hope that Italy’s most fragile might soon emerge from the pandemic.

A Nepalese woman with her child waits for a bus to go back to her village a day prior to lockdown in Kathmandu, Nepal, Wednesday, April 28, 2021. Tens of thousands of people left the Nepalese capital Wednesday a day ahead of a 15-day lockdown imposed by the government because of spiking cases of COVID-19 in the country. The lockdown has been imposed in most of the major cities and towns in the country. April 29, 2021

The governor is pushing to get 65% of Iowans vaccinated by May and 75% by June. The new efforts are meant to overcome a decline in vaccination demand, as 80 of the state’s 99 counties this week have reduced requests for shots.

The CDC says Iowa had fully vaccinated just over 1 million people, or 32% of the population, as of Wednesday. The agency says 1.4 million people, or 43% of the population, have received at least one dose.

THE VIRUS OUTBREAK

— India’s death toll surpasses 200,000; hits record 362,000 daily cases

— Chinese companies consider mixing vaccines, booster shots

— BioNTech boss: Europe will reach herd immunity this summer

— Vaccination teams in Italy visit homebound to give vaccine shots

— Follow more of AP’s pandemic coverage at https://apnews.com/hub/coronavirus-pandemic and https://apnews.com/hub/coronavirus-vaccine

HERE’S WHAT ELSE IS HAPPENING:

DETROIT — Detroit is adding to the gig economy: Drivers who take a city resident for a COVID-19 shot can get $50.

There is a $150 three-person cap per vehicle, but there’s no limit on the number of trips. Compensation will come in the form of a prepaid debit card.

“There shouldn’t be a single barrier for any Detroiter to get a vaccination, and certainly not transportation,” Mayor Mike Duggan said Wednesday.

Nearly half of Michigan residents 16 and older have received at least one shot. But in Detroit, it’s just 30%.

Drivers must register and schedule a first-dose appointment for their passenger. If they bring the person back for a second dose, they’ll get another $50 card, the city said.

Michigan continues to have the nation’s highest seven-day case rate, but the situation is improving. The seven-day daily average was 4,167, down from around 7,000 two weeks ago.

ALBUQUERQUE, N.M. — Gov. Michelle Lujan Grisham on Wednesday said she expects New Mexico to open by the end of June as long as the state reaches its goal of having at least 60% of residents fully vaccinated by then.

She made the announcement during a virtual briefing, proclaiming that the state was “conquering COVID.”

The governor and state health officials said the pace of vaccinations has been as an overwhelming driver for the progress seen in recent months, as more than 60 people are vaccinated for every new case of COVID-19 that is reported. The latest state data shows more than 41% of residents 16 and older are fully vaccinated.

“This is cause for incredible celebration,” the governor said as she predicted that New Mexico would be among the first states in the U.S. — if not the first — to have such a high percentage of its population fully vaccinated.

While capacity limits at restaurants and other businesses would be lifted once the vaccination goal is reached, the governor said COVID-safe practices will stay, including guidance on when and wear masks should be worn.

SAN FRANCISCO — California, swimming in vaccine, is in far better shape than just weeks ago when scoring an appointment was cause for celebration.

Today, Los Angeles, San Diego and other populous counties are advertising that anyone can walk in for a shot, and the state is texting reminders that plenty of appointments are available. Rural Humboldt County even declined 1,000 extra doses last week due to lackluster demand.

More than 18 million of an estimated 32 million people eligible for vaccine in California are fully or partially vaccinated, including nearly half of people in economically vulnerable ZIP codes hardest hit by the pandemic and 73% of residents 65 and older. The country’s most populous state, like much of the U.S., appears to have hit a vaccine plateau.

But that doesn’t mean everyone who wants a vaccine can get one.

Marlies Mokhtarzadeh was turned away from a downtown Millbrae pharmacy offering the one-shot Johnson & Johnson vaccine by a clerk who told her to make an appointment online. But Mokhtarzadeh, 80, isn’t able to do that and her granddaughters have also failed to book her an appointment so she’ll wait for her San Francisco Bay Area physician to get the vaccine instead.

MADRID — Spain’s health officials say that vaccination efforts are picking up pace after a record week in both the arrival of doses and the number of shots administered.

Spanish Health Minister Carolina Darias said Wednesday that the European country would receive 4 million doses of COVID-19 vaccines this week. That would be a high mark for Spain, whose vaccination campaign had suffered like the rest of the European Union from shipment delays by drugmakers.

Darias added that the 1.8 million shots administered over the past week was also a record for Spain.

Spain’s government is sticking to its pledge to get jabs in the arms of 70% of the population, some 33 million people, by the end of the summer. So far, 11.2 million of Spain’s 47 million inhabitants have received at least one shot.

Spain’s incidence rate remained steady at 230 cases per 100,000 inhabitants over 14 days. The nation’s state of emergency that has enforced mobility limitations and a nightly curfew is set to conclude on May 9.

ROME — A flight from New Delhi arrived Wednesday evening in Rome carrying 210 passengers, who will be placed in mandatory quarantine.

Officials said that a new ordinance signed earlier in the day by Health Minister Roberto Speranza requires that passengers arriving from India are quarantined for 10 days at a site indicated by Italian health officials, due to concerns about the deadly spike in that country.

The passengers were being tested upon arrival and anyone testing positive will be taken instead to a COVID hotel near Rome’s main Leonardo da Vinci International Airport. The 210 passengers include children.

Officials indicated that they were primarily Indian nationals who are residents in Italy.

DETROIT — A judge on Wednesday rejected a request to stop coronavirus testing of Michigan school athletes and other steps ordered by the state health department.

An injunction isn’t appropriate at this stage because a group called Let Them Play Michigan and its allies are unlikely to win the case, said Judge Michael Kelly of the Court of Claims.

The group argued that health department orders, especially quarantines and weekly virus testing for athletes ages 13 to 19, should have gone through a formal rule-making process.

But Kelly said state law “plainly gives” authority to the health director to issue emergency orders in response to a pandemic.

Spring lacrosse and soccer players must wear masks at all times. Athletes in baseball, golf, softball, tennis and track must wear a mask when on the sideline but not when actively competing, according to the Michigan High School Athletic Association.

MEXICO CITY — Mexico will begin bottling and packaging the Russian Sputnik V vaccine, Mexico Foreign Affairs Secretary Marcelo Ebrard said Wednesday during a visit to Russia.

Mexico has already received more than 1 million doses of Sputnik V in recent months. Ebrard says the state-owned company Birmex is working with the Russian Direct Investment Fund to prepare the bottling operations.

Mexico has already been bottling the Chinese-developed CanSino vaccine.

The domestic finishing of vaccines is part of Mexico’s efforts to obtain more shots. In addition to Sputnik V and CanSino, Mexico has been using the Pfizer, AstraZeneca and Sinovac vaccines.

The country has received 16.6 million doses and given some 12 million shots, coverng about 9.4% of the population. Mexico has vaccinated many of its senior citizens and plans to begin vaccinating people between ages 50-59 in May.

LONDON — Britain says it is buying 60 million more doses of the Pfizer coronavirus vaccine to give booster shots in the fall.

Health Secretary Matt Hancock says the new supply, which takes Britain’s total for the Pfizer shots to 100 million, will be part of the booster shot program later this year.

The government says the “most vulnerable” would be offered a booster shot before the winter, although it hasn’t identified those groups.

Britain has ordered 100 million doses of the AstraZeneca vaccine and tens of millions more of several other vaccines, not all of which have been approved for use. U.K. scientists are conducting a study on the effects of mixing different types of vaccine.

Like other countries, Britain has been hit by shortfalls in promised vaccine supplies. However, almost 65% of adults have received a dose of vaccine, while 25% have received both doses.

LONDON — Prince Charles says he is “deeply saddened” by the surge in coronavirus deaths in India and urged people to back a charity appeal to buy oxygen equipment to help the stricken nation.

In a message to the people of India, the heir to the throne says “as India has helped others, so now must we help India.”

Britain has a huge Indian diaspora community of about 1.4 million people, and many have sought to support their home country during this crisis.

The British Asian Trust, a charity Charles founded in 2007, launched an emergency appeal called “Oxygen for India” to buy oxygen concentrators, which can extract oxygen from the air when hospital infrastructure struggles to cope. The funds will be sent to the charity’s local partners in India to procure oxygen equipment for the seriously ill in both cities and harder to reach rural areas.

A first British government shipment of 200 pieces of medical equipment, including ventilators and oxygen concentrators, arrived in Delhi on Tuesday, and the rest is due to arrive by Friday.

ROME — Italy is sending India an oxygen production system that can be used to re-supply either traditional or field hospitals.

Italian Premier Mario Draghi announced Italy will send specialized personnel to guarantee the running of the system. India’s health ministry reported a record single-day 362,000 confirmed coronavirus cases on Wednesday.

Draghi expressed his “deep closeness to the Indian people” and “Italy’s support won’t be lacking in this moment of difficulty.”

This week, Italy relaxed several pandemic restrictions as daily caseloads have lowered. On Wednesday, the Italian health ministry reported 344 confirmed deaths in the last 24 hours.

Italy has Europe’s second-highest known death toll at 120,000, after Britain with 127,000.

JOHANNESBURG — South Africa has resumed giving the Johnson & Johnson vaccine to health care workers after a more than two-week pause in the use of the only vaccine in the country.

South Africa restarted its drive to inoculate its 1.2 million health care workers with the J&J vaccines as part of a large-scale study. South Africa suspended its use of the J&J vaccine on April 13 after the U.S. Food and Drug Administration reported that it might be linked to rare blood clots.

Before the halt, South Africa had given more than 290,000 shots to health care workers. Health Minister Zweli Mkhize urged all health care workers to get the vaccine.

The country’s drug regulatory body determined the J&J vaccine is safe, and the Cabinet approved resuming its use. Mkhize says the J&J vaccine is most effective against the COVID-19 variant dominant in South Africa.

With more than 1.5 million confirmed cases and 54,237 confirmed deaths, South Africa accounts for more than 30% of Africa’s 4.5 million cases and more than 40% of the 120,802 deaths, according to the Africa Centers for Disease Control and Prevention.

DHAKA, Bangladesh — Bangladesh’s Cabinet Committee on Economic Affairs on Wednesday approved in principle to produce Chinese and Russian vaccines locally to deal with the coronavirus pandemic.

Shahida Aktar, a spokeswoman for the government’s Cabinet Division, says Sputnik V and China’s Sinopharm will be produced in Bangladesh, using the facilities and logistics of different private pharmaceuticals companies.

She says Bangladesh will purchase vaccine technology directly from Russia and China to facilitate the production. The names of the Bangladeshi companies were not disclosed.

The decision came after Indian imposed ban on exporting AstraZeneca vaccines produced by Serum Institute of India amid devastating surge in India.

Also Wednesday, Bangladesh officials extended the ongoing lockdown untill May 5 across the country.

Bangladesh recorded 77 deaths and 2,955 positive cases in the last 24 hours. The nation has registered more than 754,000 confirmed cases and more than 11,000 confirmed deaths.

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